GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs3931020 | 1 | rs10874122 | chr1:75235866 | CRYZ | chr1:75171175-75199092:- | -0.29 | -4.56 | 6.83E-6 | Resistin levels |
| BLCA | cis | rs1971762 | 1 | rs10876480 | chr12:54066271 | ATP5G2 | chr12:54058945-54070512:- | 0.22 | 4.81 | 2.18E-6 | Height |
| BLCA | cis | rs1971762 | 1 | rs10876481 | chr12:54066743 | ATP5G2 | chr12:54058945-54070512:- | 0.22 | 4.81 | 2.18E-6 | Height |
| BLCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | FAM119B | chr12:58166383-58176323:+ | 0.29 | 4.44 | 1.17E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | TSFM | chr12:58176536-58191367:+ | -0.39 | -6.87 | 2.67E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.09 | 5.29E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | FAM119B | chr12:58166383-58176323:+ | 0.29 | 4.56 | 6.8E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | TSFM | chr12:58176536-58191367:+ | -0.36 | -6.51 | 2.33E-10 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -4.1 | 5.07E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.54 | 7.68E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | TSFM | chr12:58176536-58191367:+ | -0.37 | -6.73 | 6.35E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.3 | 2.21E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.32 | 2.0E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | TSFM | chr12:58176536-58191367:+ | -0.4 | -7.12 | 5.51E-12 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.2 | 3.38E-5 | Multiple sclerosis |